Discovery and development of beta2 agonists
β2-adrenoceptor agonists is a group of drugs that act selectively on β2-receptors in the lungs causing bronchodilation. β2-agonists are used to treat asthma and COPD, diseases that cause obstruction in the airways. The first β2-agonist isoproterenol, an unselective agonist which was discovered in the 1940s. The aim of the drug development through the years has been to minimise side effects, achieve selectivity and longer duration of action. The mechanism of action is well understood and has facilitated the development. The structure of the binding site and the nature of the binding is also well known, as is the structure activity relationship.
Wikipage redirect
primaryTopic
Discovery and development of beta2 agonists
β2-adrenoceptor agonists is a group of drugs that act selectively on β2-receptors in the lungs causing bronchodilation. β2-agonists are used to treat asthma and COPD, diseases that cause obstruction in the airways. The first β2-agonist isoproterenol, an unselective agonist which was discovered in the 1940s. The aim of the drug development through the years has been to minimise side effects, achieve selectivity and longer duration of action. The mechanism of action is well understood and has facilitated the development. The structure of the binding site and the nature of the binding is also well known, as is the structure activity relationship.
has abstract
β2-adrenoceptor agonists is a ...... ructure activity relationship.
@en
Link from a Wikipage to an external page
Wikipage page ID
44,298,369
Wikipage revision ID
743,995,541
hypernym
type
comment
β2-adrenoceptor agonists is a ...... ructure activity relationship.
@en
label
Discovery and development of beta2 agonists
@en