ERM protein family
The ERM protein family consists of three closely related proteins, ezrin, radixin and moesin. The three paralogs, ezrin, radixin and moesin, are present in vertebrates, whereas other species have only one ERM gene. Therefore, in vertebrates these paralogs likely arose by gene duplication. ERM proteins are highly conserved throughout evolution. More than 75% identity is observed in the N-terminal and the C-terminal of vertebrates (ezrin, radixin, moesin), Drosophila (dmoesin) and C. elegans (ERM-1) homologs.
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ERM protein family
The ERM protein family consists of three closely related proteins, ezrin, radixin and moesin. The three paralogs, ezrin, radixin and moesin, are present in vertebrates, whereas other species have only one ERM gene. Therefore, in vertebrates these paralogs likely arose by gene duplication. ERM proteins are highly conserved throughout evolution. More than 75% identity is observed in the N-terminal and the C-terminal of vertebrates (ezrin, radixin, moesin), Drosophila (dmoesin) and C. elegans (ERM-1) homologs.
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The ERM protein family consist ...... d C. elegans (ERM-1) homologs.
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Wikipage page ID
19,011,578
Wikipage revision ID
743,632,571
Caption
Crystallographic structure of the N-terminal domain of moesin.
InterPro
name
Ezrin/radixin/moesin family
comment
The ERM protein family consist ...... d C. elegans (ERM-1) homologs.
@en
label
ERM protein family
@en