Echinocandin
Echinocandins are a new class of antifungal drugs that inhibit the synthesis of glucan in the cell wall, via noncompetitive inhibition of the enzyme 1,3-β glucan synthase and are thus called "penicillin of antifungals" (a property shared with papulacandins) as penicillin has a similar mechanism against bacteria but not fungi. Beta glucans are carbohydrate polymers that are cross-linked with other fungal cell wall components (The bacterial equivalent is peptidoglycan). Caspofungin, micafungin, and anidulafungin are semisynthetic echinocandin derivatives with clinical use due to their solubility, antifungal spectrum, and pharmacokinetic properties.
Echinocandin
Echinocandins are a new class of antifungal drugs that inhibit the synthesis of glucan in the cell wall, via noncompetitive inhibition of the enzyme 1,3-β glucan synthase and are thus called "penicillin of antifungals" (a property shared with papulacandins) as penicillin has a similar mechanism against bacteria but not fungi. Beta glucans are carbohydrate polymers that are cross-linked with other fungal cell wall components (The bacterial equivalent is peptidoglycan). Caspofungin, micafungin, and anidulafungin are semisynthetic echinocandin derivatives with clinical use due to their solubility, antifungal spectrum, and pharmacokinetic properties.
has abstract
Echinocandins are a new class ...... nd pharmacokinetic properties.
@en
Equinocandinas são drogas anti ...... propriedades farmacocinéticas.
@pt
Le echinocandine sono una nuova classe di farmaci antifungini.
@it
Les échinocandines sont une cl ...... la chimie Portail de la chimie
@fr
Эхинокандины — противогрибковы ...... х фармакокинетических свойств.
@ru
الإتشينوكاندينات (بالإنجليزية: ...... الجدار الخلوي لمسببات الأمراض.
@ar
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Wikipage page ID
Wikipage revision ID
734,165,144
hypernym
type
comment
Echinocandins are a new class ...... nd pharmacokinetic properties.
@en
Equinocandinas são drogas anti ...... propriedades farmacocinéticas.
@pt
Le echinocandine sono una nuova classe di farmaci antifungini.
@it
Les échinocandines sont une cl ...... la chimie Portail de la chimie
@fr
Эхинокандины — противогрибковы ...... х фармакокинетических свойств.
@ru
الإتشينوكاندينات (بالإنجليزية: ...... الجدار الخلوي لمسببات الأمراض.
@ar
label
Echinocandin
@en
Echinocandine
@it
Equinocandina
@pt
Échinocandine
@fr
Эхинокандины
@ru
إكينوكاندين
@ar