The Francis Street-Fenwood Road Historic District encompasses a small but cohesive early 20th-century residential area and streetcar suburb in the Longwood area of Boston, Massachusetts. Bounded by Huntington Avenue, Francis Street, Vining Avenue, Fenwood Road, and St. Albans Road, it includes a collection of two and three-family houses, as well as two apartment houses, a school, and one commercial building, all of which predate the large medical complexes that dominate the Longwood area. The district was listed on the National Register of Historic Places in 2016.