Fretherne with Saul is a civil parish in the Stroud district of Gloucestershire, England. It includes the villages of Framilode, Fretherne, Saul and Upper Framilode. Watercourses form a significant portion of the parish boundaries: on two sides is the River Severn, which forms the boundary with the parishes of Westbury-on-Severn to the north and Awre to the south-west, both being in the Forest of Dean; and the Gloucester and Sharpness Canal forms the boundary with the parish of Whitminster to the east, and the major portion of the boundary with the parish of Frampton-on-Severn to the south-east. The land boundaries are with the parishes of Arlingham to the west and north-west; Frampton-on-Severn to the south; and Longney and Epney to the north-east.