George I. Wilber House is a historic home located at Oneonta in Otsego County, New York. It was built in two phases, 1875 and about 1890. It is a three story wood frame structure on a stone foundation in the Late Victorian style. It features a three story, round corner tower, cross gabled roof, and a large, very decorative wrap-around porch with a porte-cochere. In 1997 it became home to the Upper Catskill Community Council of the Arts. It was listed on the National Register of Historic Places in 2000.