Hyper IgM syndrome
Hyper IgM Syndromes is a group of primary immune deficiency disorders characterized by defective CD40 signaling by B cells affecting class switch recombination and somatic hypermutation. Immunoglobulin (Ig) class switch recombination deficiencies (CSR-Ds, which were previously named "dysgammaglobulinemia" and then "hyper-IgM syndromes") are characterized by elevated (or sometimes normal) serum Immunoglobulin M (IgM) levels and a considerable decrease in (or the absence of) Immunoglobulin G (IgG), Immunoglobulin A (IgA) and Immunoglobulin E (IgE) – suggesting defective CSR. As a consequence, patients with HIGM have decreased concentrations of serum IgG and IgA and normal or elevated IgM, leading to increased susceptibility to infections. The most common HIGM syndrome is X-linked and due to
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Hyper IgM syndrome
Hyper IgM Syndromes is a group of primary immune deficiency disorders characterized by defective CD40 signaling by B cells affecting class switch recombination and somatic hypermutation. Immunoglobulin (Ig) class switch recombination deficiencies (CSR-Ds, which were previously named "dysgammaglobulinemia" and then "hyper-IgM syndromes") are characterized by elevated (or sometimes normal) serum Immunoglobulin M (IgM) levels and a considerable decrease in (or the absence of) Immunoglobulin G (IgG), Immunoglobulin A (IgA) and Immunoglobulin E (IgE) – suggesting defective CSR. As a consequence, patients with HIGM have decreased concentrations of serum IgG and IgA and normal or elevated IgM, leading to increased susceptibility to infections. The most common HIGM syndrome is X-linked and due to
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El síndrome de hiper-IgM es un ...... ca inmunoglobulinas IgG e IgA.
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Hyper IgM Syndromes is a group ...... activated CD4+ T lymphocytes.
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Mit Hyper-IgM-Syndrom, auch Ig ...... lin A im Blutserum bezeichnet.
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Per sindrome da iper-IgM, si ...... posta da due forme specifiche.
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高免疫球蛋白M症候群是一種遺傳病，其會導致免疫球蛋白同型轉化 ...... 為X染色體隱性遺傳或體染色體隱性遺傳，視基因突變的位置而定。
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El síndrome de hiper-IgM es un ...... estinales por cryptosporidium.
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Hyper IgM Syndromes is a group ...... ndrome is X-linked and due to
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Mit Hyper-IgM-Syndrom, auch Ig ...... lin A im Blutserum bezeichnet.
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Per sindrome da iper-IgM, si ...... posta da due forme specifiche.
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高免疫球蛋白M症候群是一種遺傳病，其會導致免疫球蛋白同型轉化 ...... 為X染色體隱性遺傳或體染色體隱性遺傳，視基因突變的位置而定。
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Hyper IgM syndrome
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Hyper-IgM-Syndrom
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Sindrome da iper-IgM
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Síndrome de hiper-IgM
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高免疫球蛋白M症候群
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Hyper IgM syndrome
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