Imiglucerase
Imiglucerase is a medication used in the treatment of Gaucher's disease. It is a recombinant DNA-produced analogue of human β-glucocerebrosidase.Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is givenintravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 or 400 units per vial. The specific activity of highly purified human enzyme is 890,000 units/mg. A typical dose is 2.5U/kg every two weeks, up to a maximum of 60 U/kg once every two weeks, and safety has been established from ages 2 and up. It is one of the most expensive drugs sold, with an annual cost to U.S. patients of $200,000. Due to the low profitability (and high expense) of developing medications for rare
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Imiglucerase
Imiglucerase is a medication used in the treatment of Gaucher's disease. It is a recombinant DNA-produced analogue of human β-glucocerebrosidase.Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is givenintravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 or 400 units per vial. The specific activity of highly purified human enzyme is 890,000 units/mg. A typical dose is 2.5U/kg every two weeks, up to a maximum of 60 U/kg once every two weeks, and safety has been established from ages 2 and up. It is one of the most expensive drugs sold, with an annual cost to U.S. patients of $200,000. Due to the low profitability (and high expense) of developing medications for rare
has abstract
Imiglucerase is a medication u ...... amination with Vesivirus 2117.
@en
Imiglucerase é uma enzima util ...... sob o nome comercial Cerezyme.
@pt
Имиглуцераза (Рекомбинантная м ...... ата в США, Австралии и Японии.
@ru
イミグルセラーゼ(Imiglucerase、商品名:セレザイ ...... 認定されているためゴーシェ患者は公費負担で治療を受けられる。
@ja
ATC prefix
ATC suffix
CAS number
154248-97-2
DrugBank
FDA UNII code
Q6U6J48BWY
IUPAC name
Human Beta-glucocerebrosidase
@en
Wikipage page ID
Wikipage revision ID
744,994,960
ChEMBL
ChemSpiderID
elimination half-life
licence EU
licence US
MedlinePlus
molecular weight
5.55974e+4
routes of administration
Verifiedfields
verifiedrevid
458,273,717
hypernym
comment
Imiglucerase is a medication u ...... veloping medications for rare
@en
Imiglucerase é uma enzima util ...... sob o nome comercial Cerezyme.
@pt
Имиглуцераза (Рекомбинантная м ...... в и олигосахаридный компонент.
@ru
イミグルセラーゼ(Imiglucerase、商品名:セレザイ ...... 認定されているためゴーシェ患者は公費負担で治療を受けられる。
@ja
label
Imiglucerase
@en
Imiglucerase
@pt
Имиглуцераза
@ru
イミグルセラーゼ
@ja