Jameson Inn is an American hotel chain. The chain operates under the name Jameson Inn in the Southeastern United States, and formerly under the name Signature Inn in the Midwestern United States. Signature Inn began in 1981 in Indianapolis, Indiana, while Jameson Inn was founded in 1987 in Winder, Georgia. In 2014, Jameson Inns - along with several other ABF brands - was acquired by Vantage Hospitality.