Karin Smyth (born 8 September 1964) is a British Labour Party politician. Her parents were Irish and came to Britain in the 1950s. She was elected as the Member of Parliament (MP) for Bristol South at the 2015 general election. On 27 June 2016, she gave support to a series of shadow cabinet resignations aimed at ousting the Labour Leader, Jeremy Corbyn MP, in an open letter to constituents. She worked as an NHS manager at Bristol Clinical Commissioning Group. She was a non-executive director of Bristol North PCT from 2002 to 2006.