Kentucky Route 160, also known as KY 160, is a state highway in the U.S. state of Kentucky. It runs from the Virginia state line, where the roadway continues east to Appalachia, Virginia as State Route 160, north via Lynch, Benham, Clutts, Cumberland, Sand Hill, Gordon, Linefork, Kings Creek, Premium, and Hot Spot to Kentucky Route 15 at Van. KY 160 overlaps KY 15 through Isom to Cody, where it splits to run via Carr Creek, Brinkley, and Hindman, ending at Kentucky Route 1087 at Vest.