Laodice IV (flourished second half 3rd century BC and first half 2nd century BC) was a Greek Princess, Head Priestess and Queen of the Seleucid Empire. Antiochus III appointed Laodice in 193 BC, as the chief priestess of the state cult dedicated to her late mother Laodice III in Media. She later was married to three Kings of the Seleucid Empire, all her brothers.