Laser ablation of thyroid nodules is a minimally invasive procedure indicated to treat benign thyroid lesions such as cold nodules or single nodules within a multinodular goiter. The technique consists in the destruction of the tissue by the insertion therein of optical fibers which convey the light energy, causing a complete and not reversible lesions necrosis. The therapeutic outcome is the reduction in volume of the nodule, and as a result of local symptoms, such as compression, and reduction or loss of visibility of nodular goiter.