Little Ireland was a slum district of the township of Manchester in Lancashire in the early 19th century. It was inhabited for about 20 years from about 1827 to 1847 and was given its name from the presence of many poor Irish immigrants. It was south of Oxford Road railway station and enclosed by the railway line and the loop in the river. It is commemorated by a red plaque on 8 Great Marlborough Street, about half-way between New Wakefield Street and Hulme Street.