The Merchants and Planters Bank Building is a historic commercial building at 100 Main Street in downtown Pine Bluff, Arkansas. It is a two story brick building, with a hip roof and a turret at the northeast corner. The turret has stone arched openings at the base, providing access to the building entrance, and is topped by a bell-shaped roof. The building, designed by Thomas A. Harding of Little Rock and built in 1892, is a distinctive local example of Victorian Romanesque architecture. The building was listed on the National Register of Historic Places in 1978.