Nicodemus Mill Complex is a historic home and mill complex located at Keedysville, Washington County, Maryland, United States. It consists of a dated 1810  2 1⁄2-story, five-bay stone house with a mid-19th-century brick service wing, the ruins of a grist mill built about 1829, and an extensive complement of 19th-century domestic and agricultural outbuildings including a stone springhouse, stone-end bank barn, brick out kitchen, frame wash house, and a stuccoed stone secondary dwelling. It is an intact representative example of the type of farmstead characteristic of the region during the 19th century.