Nikolas Cassadine is a fictional character from General Hospital, an American soap opera on the ABC network. Originated by actor Tyler Christopher in 1996, he left the show on July 14, 1999. Due to Nikolas' importance on the soap, he was immediately replaced by Coltin Scott on July 20, 1999. Scott left the role on April 16, 2003, as Christopher made his return on April 21, 2003. Christopher vacated the role on July 28, 2011, after he was let go from the series. Christopher once again reprised the role on a recurring basis in honor of the soaps' fiftieth anniversary; he was later upgraded to a series regular. Actor Nick Stabile took claim of the role in June 2016 in Christopher's absence.