The strip follows the life of fictional character Claire Bennett, an insecure and naive young woman, who has left her parents' home to live on her own. She is visited frequently by Sammi, her elegant, financially savvy, and impatient best friend; Jeff, her guy's guy neighbor, who's happy working construction and doesn't understand Claire's ambition or life issues; her "out there" Oprah-fanatic mom and her "work hard or you're worth nothing" dad; and the perfect neighbors, Pasha and James, who seem to do everything with an ease and flair Claire can't achieve or imagine possessing herself. But she managed to settle down in with a life with medical researcher Paul along their dog Bradley and cat Lulu and at the end of the series were engaged.