The Pennsylvania Avenue Historic District is a residential historic district located on the 1000 block of Pennsylvania Avenue in East St. Louis, Illinois. The district includes four houses as well as the sites of two demolished homes. The historic district was once a prestigious area of the city known as "Quality Hill", and it contained well-built homes designed in popular architectural styles. However, East St. Louis entered a severe decline due to the loss of its industry, racial discrimination, and a corrupt and mismanaged city government. The historic district suffered the same fate as the city; the district is marked by vacant lots and abandoned buildings, and all but one of the houses had been vacated or demolished by the 1970s.