The Pi Chapter House of Psi Upsilon Fraternity is a building on the Syracuse University campus that was designed by W. W. Taber. It was listed on the National Register of Historic Places in 1985. It is significant for its Neoclassical design, and its historic role as "the oldest intact surviving fraternity residence at Syracuse University and for its association with the emergence of fraternal organizations as major components of Syracuse college life at the turn of the [20th] century." It is located at 101 College Place.