Piclamilast
Piclamilast (RP 73401), is a selective PDE4 inhibitor. It is comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as chronic obstructive pulmonary disease, bronchopulmonary dysplasia and asthma. It is a second generation compound that exhibits structural functionalities of the PDE4 inhibitors cilomilast and roflumilast. The structure for piclamilast was first elucidated in a 1995 European patent application. The earliest mention of the name "piclamilast" was used in a 1997 publication.
primaryTopic
Piclamilast
Piclamilast (RP 73401), is a selective PDE4 inhibitor. It is comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as chronic obstructive pulmonary disease, bronchopulmonary dysplasia and asthma. It is a second generation compound that exhibits structural functionalities of the PDE4 inhibitors cilomilast and roflumilast. The structure for piclamilast was first elucidated in a 1995 European patent application. The earliest mention of the name "piclamilast" was used in a 1997 publication.
has abstract
Piclamilast (RP 73401), is a s ...... as used in a 1997 publication.
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ATC prefix
CAS number
144035-83-6
ChEBI
DrugBank
FDA UNII code
WM58D7C3ZT
IUPAC name
3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
@en
PubChem
thumbnail
Wikipage page ID
26,952,725
Wikipage revision ID
742,434,487
ChEMBL
ChemSpiderID
molecular weight
smiles
COC1=COC3CCCC3
StdInChIKey
RRRUXBQSQLKHEL-UHFFFAOYSA-N
hypernym
comment
Piclamilast (RP 73401), is a s ...... as used in a 1997 publication.
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label
Piclamilast
@en