Powell-Redmond House is a historic home located at Clifton, Mason County, West Virginia. It was built in 1866, and is a 2 1/2 story red brick residence in the Italianate-style. It has a rear ell and features floor-length, doublehung, first story windows with heavy segmental stone lintels. The interior has a ballroom with a variety of intact ornamental plasterwork. It was built by William Henry Powell (1825–1904), who had established the Clifton Iron & Nail Company in 1866. It was listed on the National Register of Historic Places in 1983.