Punk-O-Rama 2001, Vol. 6 is the sixth compilation album in the Punk-O-Rama series. The cover is a reference to a scene in the movie 2001: A Space Odyssey, as this was the release from the year 2001. The US release of Punk-O-Rama Vol. 6 included a total of five previously unreleased tracks. The unreleased tracks are "Blackeye" by Millencolin (US only), "We're Desperate" by Pennywise, "Original Me" by Descendents, "Let Me In" by Beatsteaks and "Bath of Least Resistance" by NOFX. Pennywise perform "We're Desperate" with Exene Cervenka, who is from X which is the band that originally performed the song. "Original Me" was originally performed by ALL, which is the band the members of the Descendents formed when Milo Aukerman went to college. "Bath of Least Resistance" by NOFX was later released