The Crisp Museum, formally the Rosemary Berkel and Harry L. Crisp II Museum is a U.S. museum located on the River Campus of Southeast Missouri State University in Cape Girardeau, Missouri. It features displays and exhibitions of archaeological and historical artifacts, as well as paintings and other artworks. Originally the University Museum, the museum received its current name in 2001, and opened in its new building on the River Campus in 2007.