SB-612,111
SB-612,111 is an opioid receptor ligand which is a potent and selective antagonist for the nociceptin receptor (ORL-1), several times more potent than the older drug J-113,397. It does not have analgesic effects in its own right, but prevents the development of hyperalgesia, and also shows antidepressant effects in animal studies.
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SB-612,111
SB-612,111 is an opioid receptor ligand which is a potent and selective antagonist for the nociceptin receptor (ORL-1), several times more potent than the older drug J-113,397. It does not have analgesic effects in its own right, but prevents the development of hyperalgesia, and also shows antidepressant effects in animal studies.
has abstract
SB-612,111 is an opioid recept ...... ant effects in animal studies.
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CAS number
371980-98-2
IUPAC name
(5S,7S)-7-{[4-(2,6-dichlorophe ...... ahydro-5H-benzo[7]annulen-5-ol
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PubChem
thumbnail
Wikipage page ID
20,147,598
Wikipage revision ID
701,952,613
ChEMBL
ChemSpiderID
IUPHAR ligand
molecular weight
4.18398e+2
smiles
CC1=C2CC[C@@H]CN3CCCC4=CCl
CC1=CC=CC2=C1CC[C@@H]CN3CCCC4=CCl
StdInChIKey
OHRDCQFCAWLDBP-SBUREZEXSA-N
synonyms
Verifiedfields
verifiedrevid
399,128,757
comment
SB-612,111 is an opioid recept ...... ant effects in animal studies.
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label
SB-612,111
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