St. Joseph's High School (commonly referred to as "St. Joe") was a fully accredited Catholic high school located at 601 Fox Street in Denver, Colorado, United States. It was one of several parochial high schools in the Denver Metropolitan Area. Saint Joseph High School served students in grades 9 through 12. The entire student body averaged less than 300 students. This small school size may have contributed to their tremendous pride. It was built in one of the original settlement areas of historic Denver. The adjoining Saint Joseph Church is on the National Register of Historic Places.