"Screams of Silence: The Story of Brenda Q" is the third episode of the tenth season of the animated comedy series Family Guy. It originally aired on October 30, 2011 in the United States on Fox. The episode follows Griffin family neighbor Glenn Quagmire's sister, Brenda, as she struggles with physical and mental abuse at the hands of her boyfriend, and eventual fiancé, Jeff. Quagmire, along with his neighbors, Peter and Joe, seek to relieve Brenda from her anguish, and soon decide to murder him, in order to prevent her from being harmed any further.