The Wellman Building, also known as the Wellman Block, is a historic commercial building located at Jamestown in Chautauqua County, New York. It consists of an 1897 masonry bearing wall structure and a steel frame structure built in 1910. The 1897 building is a five story, Renaissance Revival brick building. The 1910 addition retains the Renaissance Revival style. The building originally housed a druggist and stationery store on the first floor, with offices on the upper floors. It was listed on the National Register of Historic Places in 2009.