Tiff City is an unincorporated community in McDonald County, Missouri, United States. It is located on Route 76 next to the Oklahoma state line. It was named for barite ore found near, also known as "tiff". The community is part of the Fayetteville–Springdale–Rogers, AR-MO Metropolitan Statistical Area. Tiff City is a small community with only four businesses. It has a post office, a bank, a convenience store/gas-diesel pumps, and a liquor store. There is also a church and community center building.