Transcription activator-like effector nuclease
Transcription activator-like effector nucleases (TALEN) are restriction enzymes that can be engineered to cut specific sequences of DNA. They are made by fusing a TAL effector DNA-binding domain to a DNA cleavage domain (a nuclease which cuts DNA strands). Transcription activator-like effectors (TALEs) can be engineered to bind practically any desired DNA sequence, so when combined with a nuclease, DNA can be cut at specific locations. The restriction enzymes can be introduced into cells, for use in gene editing or for genome editing in situ, a technique known as genome editing with engineered nucleases. Alongside zinc finger nucleases and CRISPR/Cas9, TALEN is a prominent tool in the field of genome editing.
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Transcription activator-like effector nuclease
Transcription activator-like effector nucleases (TALEN) are restriction enzymes that can be engineered to cut specific sequences of DNA. They are made by fusing a TAL effector DNA-binding domain to a DNA cleavage domain (a nuclease which cuts DNA strands). Transcription activator-like effectors (TALEs) can be engineered to bind practically any desired DNA sequence, so when combined with a nuclease, DNA can be cut at specific locations. The restriction enzymes can be introduced into cells, for use in gene editing or for genome editing in situ, a technique known as genome editing with engineered nucleases. Alongside zinc finger nucleases and CRISPR/Cas9, TALEN is a prominent tool in the field of genome editing.
has abstract
Décrits pour la première fois ...... ur modifier le génome in situ.
@fr
Eine Transcription activator-l ...... pezifisches Restriktionsenzym.
@de
TALENs são fusões de proteínas ...... tipos de células e organismos.
@pt
Transcription activator-like e ...... n the field of genome editing.
@en
類轉錄活化因子核酸酶(英语:Transcription ac ...... NA顺序。当这些限制酶被引入细胞,可被用来做基因組原位编辑。
@zh
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Décrits pour la première fois ...... t la capacité de cliver l'ADN.
@fr
Eine Transcription activator-l ...... pezifisches Restriktionsenzym.
@de
TALENs são fusões de proteínas ...... tipos de células e organismos.
@pt
Transcription activator-like e ...... n the field of genome editing.
@en
類轉錄活化因子核酸酶(英语:Transcription ac ...... NA顺序。当这些限制酶被引入细胞,可被用来做基因組原位编辑。
@zh
label
TALEN
@pt
Transcription Activator-like Effector Nuclease
@de
Transcription activator-like effector nuclease
@en
Transcription activator-like effector nuclease
@fr
類轉錄活化因子核酸酶
@zh