Trovafloxacin
Trovafloxacin (sold as Trovan by Pfizer and Turvel by Laboratorios Almirall) was a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was withdrawn from the market due to the risk of hepatotoxicity. It had better gram-positive bacterial coverage and less gram-negative coverage than the previous fluoroquinolones.
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Trovafloxacin
Trovafloxacin (sold as Trovan by Pfizer and Turvel by Laboratorios Almirall) was a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was withdrawn from the market due to the risk of hepatotoxicity. It had better gram-positive bacterial coverage and less gram-negative coverage than the previous fluoroquinolones.
has abstract
A trovafloxacina (Trovan®) é u ...... gado (hepatite medicamentosa).
@pt
La trovafloxacina o trovafloxa ...... legale (Contenzioso di Kano).
@it
La trovafloxacine (Trovan) est ...... ues (hépatite médicamenteuse).
@fr
Trovafloxacin (sold as Trovan ...... the previous fluoroquinolones.
@en
Trovafloxacina (comercializado ...... obre bacterias gram negativas.
@es
تروفافلوكساسين (Trovafloxacin) ...... سبب الخطر الذي يسبب على الكبد.
@ar
ATC prefix
ATC suffix
CAS number
147059-72-1
DrugBank
FDA UNII code
9F388J00UK
IUPAC name
7-(6-Amino-3-azabicyclo[3.1.0] ...... aphthyridine-3-carboxylic acid
@en
PubChem
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Link from a Wikipage to an external page
Wikipage page ID
Wikipage revision ID
743,149,060
ChemSpiderID
16,736,478
legal status
Withdrawn from market
MedlinePlus
molecular weight
4.16353e+2
routes of administration
Oral, intravenous
smiles
O=CC2=CNc5ccccc5F
StdInChIKey
WVPSKSLAZQPAKQ-CDMJZVDBSA-N
Verifiedfields
verifiedrevid
470,618,270
Watchedfields
comment
A trovafloxacina (Trovan®) é u ...... gado (hepatite medicamentosa).
@pt
La trovafloxacina o trovafloxa ...... girasi e la topoisomerasi IV.
@it
La trovafloxacine (Trovan) est ...... ues (hépatite médicamenteuse).
@fr
Trovafloxacin (sold as Trovan ...... the previous fluoroquinolones.
@en
Trovafloxacina (comercializado ...... obre bacterias gram negativas.
@es
تروفافلوكساسين (Trovafloxacin) ...... سبب الخطر الذي يسبب على الكبد.
@ar
label
Trovafloxacin
@en
Trovafloxacina
@es
Trovafloxacina
@it
Trovafloxacina
@pt
Trovafloxacine
@fr
تروفافلوكساسين
@ar