TxpA-RatA toxin-antitoxin system
The TxpA/RatA toxin-antitoxin system was first identified in Bacillus subtilis. It consists of a non-coding 222nt sRNA called RatA (RNA anti-toxin A) and a protein toxin named TxpA (Toxic protein A). RatA was discovered in intergenic regions of the B. subtilis genome, in a 728-nucleotide region between genes yqdB (later renamed TxpA) and yqbM. Initially, Affymetrix microarrays were used to detect transcription in this region, Northern blot experiments and mutation analysis were then employed to characterise the RNA transcript.
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TxpA-RatA toxin-antitoxin system
The TxpA/RatA toxin-antitoxin system was first identified in Bacillus subtilis. It consists of a non-coding 222nt sRNA called RatA (RNA anti-toxin A) and a protein toxin named TxpA (Toxic protein A). RatA was discovered in intergenic regions of the B. subtilis genome, in a 728-nucleotide region between genes yqdB (later renamed TxpA) and yqbM. Initially, Affymetrix microarrays were used to detect transcription in this region, Northern blot experiments and mutation analysis were then employed to characterise the RNA transcript.
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The TxpA/RatA toxin-antitoxin ...... or blocks cell wall synthesis.
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Wikipage page ID
28,842,855
Wikipage revision ID
724,030,275
Caption
Conserved secondary structure of RatA antitoxin sRNA.
name
RNA anti-toxin A
RNA type
Tax domain
subject
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The TxpA/RatA toxin-antitoxin ...... aracterise the RNA transcript.
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label
TxpA-RatA toxin-antitoxin system
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