USS Mary Pope (SP-291) was a United States Navy patrol vessel in commission from 1917 to 1919. Mary Pope was built as the civilian wooden-hulled motorboat Manitee in 1915 by the Gas Engine and Power Company and the Charles L. Seabury Company at Morris Heights in the Bronx, New York. She later was renamed Madge and then Mary Pope. The U.S. Navy purchased Mary Pope from her owner, R. W. Bingham, on 7 July 1917 for World War I service as a patrol vessel. She was commissioned on 9 August 1917 as USS Mary Pope (SP-291). Mary Pope operated on section patrol duties for the rest of World War I.