Vintafolide
Vintafolide is an investigational targeted cancer therapeutic currently under development by Endocyte and Merck & Co. It is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor, which is overexpressed on certain cancers, such as ovarian cancer, and a potent chemotherapy drug, vinblastine. Vintafolide is designed to deliver the toxic vinblastine drug selectively to cells expressing the folate receptor using folate targeting.
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Vintafolide
Vintafolide is an investigational targeted cancer therapeutic currently under development by Endocyte and Merck & Co. It is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor, which is overexpressed on certain cancers, such as ovarian cancer, and a potent chemotherapy drug, vinblastine. Vintafolide is designed to deliver the toxic vinblastine drug selectively to cells expressing the folate receptor using folate targeting.
has abstract
Vintafolide is an investigatio ...... ove progression-free survival.
@en
ATC prefix
ATC suffix
CAS number
742092-03-1
IUPAC name
N-(4-{[(2-Amino-4-oxo-1,4-dihy ...... cino[5,4-b]indol-9-carboxylate
@en
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Wikipage page ID
35,530,476
Wikipage revision ID
709,642,563
Alt
Vintafolide structure
ChemSpiderID
27,444,385
legal status
molecular weight
smiles
[H]/N=C/NCCC[C@@H]NC[C@H]NCCC[C@@H]NCc1cccNCc1cnc2cc[nH]cN
StdInChIKey
KUZYSQSABONDME-QRLOMCMNSA-N
synonyms
hypernym
comment
Vintafolide is an investigatio ...... ceptor using folate targeting.
@en
label
Vintafolide
@en
