"Who's Gonna Save My Soul" is the third and final single taken from hip-hop duo Gnarls Barkley's second studio album, The Odd Couple, released in late 2008. The song's official music video was directed by Chris Milk and was released on July 25, 2008. The video featured work by character animator Keith Sintay. The single was only released physically in America, in a special limited edition CD + DVD single package.