1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually handled as the hydrochloride. It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds. Additionally, EDC can also be used to activate phosphate groups in order to form phosphomonoesters and phosphodiesters. Common uses for this carbodiimide include peptide synthesis, protein crosslinking to nucleic acids, but also in the preparation of immunoconjugates. EDC is often used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules. Recent work has also used EDC to assess the structure state of uracil nucleobases in RNA.
1-ethyl-3-(3-dimethylaminopropyl)carbodiimide1-ethyl-3-3(3-dimethylaminopropyl) carbodiimide hydrochlorideBiotin PEG2 amineBiotinylationBottromycinChemical modificationEDACEDCEDCIEdclEthyl(dimethylaminopropyl) carbodiimideEthyl cyanohydroxyiminoacetateHBTUKeyhole limpet hemocyaninList of MeSH codes (D02)N,N'-DicyclohexylcarbodiimideN-HydroxysuccinimideNucleic acid structure determinationPeptide synthesisSaxagliptinTissue engineering
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1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually handled as the hydrochloride. It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds. Additionally, EDC can also be used to activate phosphate groups in order to form phosphomonoesters and phosphodiesters. Common uses for this carbodiimide include peptide synthesis, protein crosslinking to nucleic acids, but also in the preparation of immunoconjugates. EDC is often used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules. Recent work has also used EDC to assess the structure state of uracil nucleobases in RNA.
has abstract
1-Ethyl-3-(3-dimethylaminoprop ...... of uracil nucleobases in RNA.
@en
1-Этил-3-(3-диметиламинопропил ...... тализатора применяется (DMAP).
@ru
1-乙基-3-(3-二甲基氨基丙基)碳酰二亚胺(亦稱为EDC ...... 4-二甲氨基吡啶(DMAP)搭配使用作为羧酸和醇的酯化试剂。
@zh
Ethyl(dimethylaminopropyl)karb ...... mobilizaci velkých biomolekul.
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La EDC (también EDAC o EDCI, a ...... ohol, usando como catalizador.
@es
Le 1-éthyl-3-(3-diméthylaminop ...... xation de larges biomolécules.
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IUPAC name
3-{[(Ethylimino)methylidene]amino}-N,N-dimethylpropan-1-amine
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Ball-and-stick model of the EDC molecule
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Skeletal formula of EDC
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verifiedrevid
477,207,658
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hypernym
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1-Ethyl-3-(3-dimethylaminoprop ...... of uracil nucleobases in RNA.
@en
1-Этил-3-(3-диметиламинопропил ...... льзуется при pH от 4,0 до 6,0.
@ru
1-乙基-3-(3-二甲基氨基丙基)碳酰二亚胺(亦稱为EDC ...... 4-二甲氨基吡啶(DMAP)搭配使用作为羧酸和醇的酯化试剂。
@zh
Ethyl(dimethylaminopropyl)karb ...... mobilizaci velkých biomolekul.
@cs
La EDC (también EDAC o EDCI, a ...... s estables reactivos a aminas.
@es
Le 1-éthyl-3-(3-diméthylaminop ...... roxysuccinimide (NHS) pour la
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label
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimid
@de
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
@en
1-etil-3-(3-dimetilaminopropil)carbodiimida
@es
1-Éthyl-3-(3-diméthylaminopropyl)carbodiimide
@fr
1-Этил-3-(3-диметиламинопропил)карбодиимид
@ru
1-乙基-(3-二甲基氨基丙基)碳酰二亚胺
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Ethyl(dimethylaminopropyl)karbodiimid
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Etil-3-(3-dimetilaminopropil)carbodiimida
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