14-Methoxydihydromorphinone
14-Methoxydihydromorphinone is a semi-synthetic opioid related to 14-methoxymetopon (14-MM), an opioid with a Ki of 0.15 nM, and (14-OMO) with a Ki of 0.10 nM. By contrast, oxymorphone has a Ki of 0.97 nM and morphine one of 6.55 nM (all at mu receptors). This suggests that both 14-OMO and 14-MM have a higher mu/kappa selectivity than oxymorphone.
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14-Methoxydihydromorphinone
14-Methoxydihydromorphinone is a semi-synthetic opioid related to 14-methoxymetopon (14-MM), an opioid with a Ki of 0.15 nM, and (14-OMO) with a Ki of 0.10 nM. By contrast, oxymorphone has a Ki of 0.97 nM and morphine one of 6.55 nM (all at mu receptors). This suggests that both 14-OMO and 14-MM have a higher mu/kappa selectivity than oxymorphone.
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14-Methoxydihydromorphinone is ...... selectivity than oxymorphone.
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IUPAC name
(4R,4aS,7aR,12bS)-9-Hydroxy-4a ...... o[3,2-e]isoquinolin-7(7aH)-one
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(5α)-3-Hydroxy-14-methoxy-17-methyl-4,5-epoxymorphinan-6-one
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47,715,463
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1,017,967,087
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14-Methoxydihydromorphinone is ...... selectivity than oxymorphone.
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label
14-Methoxydihydromorphinone
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