The 16th Texas Cavalry Regiment was a unit of mounted volunteers from Texas that fought in the Confederate States Army during the American Civil War. The regiment was recruited in early 1862 and mustered into Confederate service in April 1862. The unit fought as cavalry at the Battle of Cotton Plant but it was dismounted in the summer of 1862. The 16th Cavalry served as infantry in Walker's Texas Division for the remainder of the war. The regiment fought at Milliken's Bend, Mansfield, Pleasant Hill, and Jenkins' Ferry. The unit marched to Texas in early 1865 and disbanded in May 1865.