The 1862 Pacific Northwest smallpox epidemic was a smallpox outbreak that started in Victoria on Vancouver Island and spread among the indigenous peoples of the Pacific Northwest Coast and into the indigenous peoples of the Northwest Plateau, killing a large portion of natives from the Puget Sound region to Southeast Alaska. The epidemic marks a major turning point in Pacific Northwest history and devastated indigenous nations. The death rate was highest in southeast Alaska and Haida Gwaii—over 70% among the Haida and 60% among the Tlingit. Almost all native nations along the coast, and many in the interior, were devastated, with a death rate of over 50% for the entire coast from Puget Sound to Sitka, Alaska, part of Russian America at the time. In some areas the native population fell by