The 1916 Kendall Orange and Black football team represented Henry Kendall College, which was later renamed the University of Tulsa, during the 1916 college football season. In their fourth year under head coach Sam P. McBirney, the Orange and Black compiled a 10–0 record, won the Oklahoma Intercollegiate Conference championship, shut out five of ten opponents, and outscored their opponents by a combined total of 566 to 40, including high-scoring wins against Missouri Mines (117–0), St. Gregory's (82–0), Arkansas Cumberland (81–0), and Haskell (46–0).