The 1921 Michigan Wolverines football team represented the University of Michigan in the 1921 Big Ten Conference football season. In his 21st year as head coach, Fielding H. Yost led Michigan to a 5–1–1 record, as the Wolverines outscored their opponents with a combined score of 187 to 21. Michigan recorded shutouts in five of its seven games, allowing only 14 points in a loss to Ohio State and 7 points in a tie with Wisconsin. Over the course of five home games at the newly expanded Ferry Field, the Wolverines attracted crowds totaling 143,500 with receipts totaling $170,000.