The 1946 Big Nine Conference football season was the 51st season of college football played by the member schools of the Big Nine Conference (also known as the Big Ten Conference and the Western Conference) and was a part of the 1946 college football season. Indiana, under head coach Bo McMillin, compiled a 6–3 record, finished third in the conference, and was ranked No. 20 in the final AP Poll. End Pete Pihos received the team's most valuable player award. Quarterback Ben Raimondi won first team All-Big Nine honors.