The 2000 LPGA Championship was the 46th LPGA Championship, played June 22–25 at DuPont Country Club in Wilmington, Delaware. This was the second of four major championships on the LPGA Tour in 2000. Defending champion Juli Inkster won her second consecutive LPGA Championship on the second hole of a sudden-death playoff with Stefania Croce, and became the first to successfully defend the title since 1984. The DuPont Country Club hosted this championship for eleven consecutive seasons, from 1994 through 2004.