The 2018 William Hill US Darts Masters was the second staging of the tournament by the Professional Darts Corporation. It was the second event in the 2018 World Series of Darts. The tournament featured 16 players (8 PDC representatives and 8 North American representatives) and was held at the Mandalay Bay in Las Vegas on 6–7 July 2018. Michael van Gerwen was the defending champion after defeating Daryl Gurney 8–6 in the 2017 final. However, he lost 8–3 in the quarter-finals to James Wade. Gary Anderson won his sixth World Series title after beating Rob Cross 8–4 in the final.