3,4-Dichloroamphetamine
3,4-Dichloroamphetamine (DCA), is an amphetamine derived drug invented by Eli Lilly in the 1960s, which has a number of pharmacological actions. It acts as a highly potent and selective serotonin releasing agent (SSRA) and binds to the serotonin transporter with high affinity, but also acts as a selective serotonergic neurotoxin in a similar manner to the related para-chloroamphetamine, though with slightly lower potency. It is also a monoamine oxidase inhibitor (MAOI), as well as a very potent inhibitor of the enzyme phenylethanolamine N-methyl transferase which normally functions to transform noradrenaline into adrenaline in the body.
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3,4-Dichloroamphetamine
3,4-Dichloroamphetamine (DCA), is an amphetamine derived drug invented by Eli Lilly in the 1960s, which has a number of pharmacological actions. It acts as a highly potent and selective serotonin releasing agent (SSRA) and binds to the serotonin transporter with high affinity, but also acts as a selective serotonergic neurotoxin in a similar manner to the related para-chloroamphetamine, though with slightly lower potency. It is also a monoamine oxidase inhibitor (MAOI), as well as a very potent inhibitor of the enzyme phenylethanolamine N-methyl transferase which normally functions to transform noradrenaline into adrenaline in the body.
has abstract
3,4-Dichloroamphetamine (DCA), ...... e into adrenaline in the body.
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CAS number
ChEMBL
FDA UNII code
4Q81NBO3IA
PubChem
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33,815,651
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1,003,129,188
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ATC prefix
none
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CAS number
ChEMBL
ChemSpiderID
IUPAC name
PubChem
SMILES
Clc1ccccc1Cl
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StdInChIKey
PUFDZMUCDFIRQY-UHFFFAOYSA-N
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Verifiedfields
changed
@en
verifiedrevid
477,344,465
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hypernym
comment
3,4-Dichloroamphetamine (DCA), ...... e into adrenaline in the body.
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label
3,4-Dichloroamphetamine
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