5-Hydroxycytosine
5-Hydroxycytosine is an oxidized form of cytosine that is associated with an increased frequency of C to T transition mutations, with some C to G transversions. It does not distort the DNA molecule and is readily bypassed by replicative DNA polymerases. It has been shown in vitro to miscode for adenine. 5-hydroxycytosine is imperitive for parallel DNA triplex formation, explaining why parallel triplexes form only at pH 6 and below.
Wikipage redirect
Link from a Wikipage to another Wikipage
primaryTopic
5-Hydroxycytosine
5-Hydroxycytosine is an oxidized form of cytosine that is associated with an increased frequency of C to T transition mutations, with some C to G transversions. It does not distort the DNA molecule and is readily bypassed by replicative DNA polymerases. It has been shown in vitro to miscode for adenine. 5-hydroxycytosine is imperitive for parallel DNA triplex formation, explaining why parallel triplexes form only at pH 6 and below.
has abstract
5-Hydroxycytosine is an oxidiz ...... s form only at pH 6 and below.
@en
alternative name
4-Amino-5-hydroxypyrimidine-2-one
@en
IUPAC name
4-Amino-5-hydroxypyrimidin-2(1H)-one
@en
Wikipage page ID
47,292,282
page length (characters) of wiki page
Wikipage revision ID
1,019,290,362
Link from a Wikipage to another Wikipage
ImageFile
imagesize
OtherNames
wikiPageUsesTemplate
subject
hypernym
comment
5-Hydroxycytosine is an oxidiz ...... s form only at pH 6 and below.
@en
label
5-Hydroxycytosine
@en