An absolute configuration refers to the spatial arrangement of the atoms of a chiral molecular entity (or group) and its stereochemical description. A chiral carbon is bonded to four different substituents, which can be arranged in two different ways, creating two enantiomers. Absolute configuration uses a set of rules to describe the relative positions of bonds on chiral centers. When the absolute configuration is obtained, the assignment of the descriptors R or S is based on the Cahn–Ingold–Prelog priority rules. R and S refer to Rectus and Sinister, respectively, which are Latin for right and left.