Alexandria in Orietai was one of the seventy-plus cities founded or renamed by Alexander the Great. The town was founded by Alexander in autumn of 325 BC after his army had separated from Nearchus and the boats near the mouth of the Indus River. The sources agree that a town was built among the Oreitians, that the fortification was left to Hephaestion and Leonnatus be built in the autumn of 325 BC and that it was located near Rhambacia, the largest town of the Oreitai. The core of colonists were retired Arachosian horsemen.