Alfons Maria Jakob (2 July 1884 – 17 October 1931) was a German neurologist who worked in the field of neuropathology. He was born in Aschaffenburg, Bavaria and educated in medicine at the universities of Munich, Berlin, and Strasbourg, where he received his doctorate in 1908. During the following year, he began clinical work under the psychiatrist Emil Kraepelin and did laboratory work with Franz Nissl and Alois Alzheimer in Munich.