The American Sugar Refining Company (ASR) was the largest American business unit in the sugar refining industry in the early 1900s. It had interests in Puerto Rico and other Caribbean locations, and operated one of the world's largest sugar refineries, the Domino Sugar Refinery in Brooklyn, New York. The Domino brand name was acquired in 2001 by Florida Crystals Corporation and rebranded as American Sugar Refining, a new company created in 1998 and unrelated to the prior firm by that name.